AI is built for what’s next. Most enterprise technology was built for what was.
Seventy percent of Fortune 500 legacy software is more than 20 years old, while the same share of enterprise workloads still run on premises. That’s a lot of AI ambition riding on yesterday’s engine.
Our work with AWS is growing fast. So is what we’re building together. At re:Invent, we’re bringing two new plays: modernize what holds you back and build what puts you ahead.
Where you can find us at AWS re:Invent
Parked at booth #1940.
Start here. See the plays. Meet the people.
Leave legacy in the dust.
Beyond search: How Gilead built a multi-agent AI that reasons like a scientist
Gilead is pivoting from virology leader to oncology and immunology powerhouse, targeting 10+ transformative therapies by 2030. With Thoughtworks, Gilead built an AI co-scientist on AWS that reasons across 1M+ ELN assay records, 3M+ internal documents and external literature.
It reads assay, compound and target data like a scientist, returning one cited answer with conflicts flagged. Scientists now reach evidence-backed decisions in minutes, not days. Gilead and Thoughtworks share how the solution earned scientists' trust.
Timing: Wednesday December 2, 2026 at 11:00am
Location: Lightning Theater in the Venetian Expo | AWS for Industries
Speakers: Shayan Mohanty (Chief Data and AI Officer, Thoughtworks) and Sachin Sontakke (Executive Director, Data and AI COE, Gilead)
How to achieve ROI with agentic engineering
Join Thoughtworks and Platform Engineering community for an executive breakfast. Over breakfast, we’ll explore what those organizations do differently to enable agentic engineering securely, with high trust and accountability.
We’ll discuss:
Platform readiness: why it’s the biggest blocker to scaling AI in the enterprise, more than model availability.
What the 8% changed: the technical and cultural shifts they made to navigate cost, agent identity and more to reach transformational ROI.
Output vs. value: why more output doesn’t automatically mean more value, and where your teams should focus instead.
Hosts: Rickey Zachary, Global Engineering Platforms Lead at Thoughtworks and Sam Barlien, Head of Ecosystem at Platform Engineering
Timing: Tuesday December 1, 2026 at 8:00am
Location: The Westin, 160 E Flamingo Rd, Las Vegas
Lose the legacy. Gain the advantage.
Two new plays from Thoughtworks and AWS. Your move.
Play 1: Modernize what holds you back with AI/works™ and AWS Transform
Legacy mainframe, .NET and bespoke applications add friction to everything you build next. Thoughtworks AI/works™ and AWS Transform help you understand, refactor and modernize them; incrementally and without putting progress on hold.
For: CIOs, CTOs and technology leaders driving modernization
Play 2: Build what puts you ahead with AWS Agentic Catalyst and 3/3/3
Agentic ideas shouldn’t need a year to prove their value. The AWS Agentic Catalyst Program and Thoughtworks’ 3/3/3 method take you from idea to prototype and costed business case in days, then into production as a minimum lovable product.
For: Leaders and builders across product, innovation, AI and engineering.
Shift into Happy Hour
Trade the conference floor for premium cocktails, passed hors d’oeuvres and a retro arcade at the TAO Opium Room at The Venetian.
Space is limited. Your evening doesn’t have to be.
Date: December 1, 2026
Time: 6:00pm to 8:00pm
Three minutes. Two races. One goal: leave legacy in the rearview.
Take the controls at Booth #1940 and put our plays (and your skills) to the test. Race the clock, climb the leaderboard and meet the people building the real-world solutions behind the game.
More of what we do with AWS
Recognized by AWS for delivering impact
In 2025 Thoughtworks was recognized as the AWS global partner of the year for data and analytics. This award celebrates the teams turning complex, fragmented data into the governed foundation that makes AI ready to act for clients worldwide.
It's proof of what this partnership does every day, translating data strategy into measurable business outcomes at enterprise scale.
Some problems deserve more than a booth chat
Want to go deeper than a booth conversation? Book time with our Thoughtworks and AWS team at re:Invent to talk modernization, agentic AI or whatever is standing between you and what’s next.